Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.

نویسندگان

  • Tian-Cheng Li
  • Sayaka Yoshizaki
  • Yasushi Ami
  • Yuriko Suzaki
  • Tingting Yang
  • Naokazu Takeda
  • Wakita Takaji
چکیده

Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by intravenous injection. None of the animals demonstrated a positive sign for virus replication, indicating that rats and monkeys are not susceptible to ferret HEV.

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Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection

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عنوان ژورنال:
  • Intervirology

دوره 58 3  شماره 

صفحات  -

تاریخ انتشار 2015